Alexis Turgeon-Fournier

• Centre de recherche du CHU de Québec - Université Laval

Financements des 2 dernières années

• Anne Saint-Laurent, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Fannie Decoste, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Farnaz Naeimzadeh, Stage postdoctoral en médecine
• Kendy Imrith, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Marie-Pier Clément, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Stacey Thivierge, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire

Encadrements des 5 dernières années

• Alexandre Bergeron, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Claudya Morin, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Elisabeth Canitrot, Doctorat en épidémiologie
• Frédérique Lamothe Boucher, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Marwan Maxime Bouras, Stage postdoctoral en médecine
• Mauricio Umana Perea, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Nicolas Beaulieu, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Noémie Villemure-Poliquin, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Philippe Boisvert, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire
• Thierry Rouleau-Bonenfant, Maîtrise en épidémiologie - épidémiologie clinique - avec mémoire

Travaux de recherche des 5 dernières années

Effectiveness of Selective Cyclooxygenase-2 Inhibitors for Postoperative Pain Management Using Multidimensional Pain Assessment: A Systematic Review and Meta-analysis of Randomized Controlled Trials Anesthesiology, 2026. Usman Kahloon, Sarah Tierney, Dean A. Fergusson, Manoj M. Lalu, Daniel I. McIsaac, Alexis F. Turgeon, Sanskruti Patel, Stephanie Musa, Michael Verret, John B. P. Le. DOI 10.1097/ALN.0000000000006216

Individualised positive end-expiratory pressure to minimise driving pressure and postoperative pulmonary complications in minimally invasive thoracic and abdominal surgery a systematic review and meta-analysis British Journal of Anaesthesia, 2026. Megan Abbott, Richard Ma, Hawwa Chakera, Teruko Kishibe, Martin Girard, Alexis F. Turgeon, Ary Serpa Neto, Michael C. Sklar, Ashwin Sankar. DOI 10.1016/j.bja.2026.02.036

The effectiveness of selective COX-2 inhibitors for postoperative pain management using multidimensional pain assessment: A systematic review and meta-analysis of randomized controlled trials Anesthesiology, 2026. Usman Kahloon, John B.P. Le, Sarah Tierney, Dean A. Fergusson, Manoj M. Lalu, Daniel I. McIsaac, Alexis F. Turgeon, Sanskruti Patel, Stephanie Musa, Michael Verret.

Reconsidering transfusion thresholds in traumatic brain injury with multiple trauma: implications from the HEMOTION sub-study. Author’s reply Intensive Care Medicine, 2026. Marwan Bouras, François Lauzier, Dean A. Fergusson, Xavier Neveu, Alexis F. Turgeon. DOI 10.1007/s00134-026-08485-4

Prevalence, semiology and neuroimaging of movements in comatose adults at risk of death by neurologic criteria: a prospective cohort study Critical Care, 2026. Joel Neves Briard, Shane W. English, Dean A. Fergusson, Sonny Dhanani, François Lauzier, Alexis F. Turgeon, Ian Ball, Sultan Darvesh, Polina Titova, Martine Lebrasseur, Philippe Couillard, Andreas Kramer, Frédérick D’Aragon, Mathew Hannouche, Karen E. A. Burns, J. Gordon Boyd, Alexandra Binnie, Han Ting Wang, Sam Shemie, Jai Jai Shiva Shankar, Michaël Chassé, Pierre Aslanian, Sylvain Belisle, François Martin Carrier, Pierre-Marc Chagnon, Annick Chatillon, Daniel Corsilli, Julie Cousineau, Tudor Costacescu, Marc-Jacques Dubois, Andréa Gagnon-Hamelin, Mélissa Gagnon-Hamelin, Martin Girard, François Guilbert, Jean-Gilles Guimond, Christophe Kolan, Dominique Lafrance, Francesca Lamothe, Jean-François Lizé, Nicholas Robillard, Catalina Sokoloff, David Bellemare, Jean-Luc Gariépy, Stéphanie Grenier, Gabrielle Guilbaut, Marie-Pier Bouchard, Élaine Charbonneau, Jean Chénard, François Lamontagne, Charles St-Arnaud, Cassidy Codan, Olesya Dmitrieva, Muneer Eesa, Lily Guan, Julie Kromm, Lori Hand, Draga Jichici, Bijoy K. Menon, Arun Mensinkai, Andrée-Anne Pistono, Danaë Tassy, Tracy Boyd, Miranda Hunt, Omar Islam, Tracey Bental, Michael Jurkiewicz, Claudio Martin, Marat Slessarev, Faisal Siddiqui, Khunza Faiz, Nicole Marten, Maggie Wilson, Susan Alcock, Marco Essig, Ryan Zarychanski, Josie Campisi, Jeffrey Chankowsky, Kosar Khwaja, Raham Rahgoshai, Jason Shahin, Maureen O. Meade, Erin Cole, Rick Sanchez, Donatella Tampieri, Catherine Therrien, Gilbert Yip, Valerie Barette, Robert Green, Laura Magennis, Matthias Schmidt, Robert Vandorpe, Andrew J. Baker, Aditya Bharatha, Imrana Khalid, Gyan Sandhu, Marlene Santos, Santanu Chakraborty, Jessica Haines, Greg Knoll, Doug McGuire, Rebecca Porteous, Irene Watpool, Kusum Menon, Noha Aref, Andrew Gibson, Vinayak Lad, Rosa Myrna Marticorena, Marc Ossip. DOI 10.1186/s13054-026-06037-2

Global Recognition of Traumatic Brain Injury as a Chronic and Notifiable Condition: A Post-WHA78 Advocacy Commentary Brain Sciences, 2026. Almas F. Khattak, Saniya Mediratta, Sara Venturini, Brandon George Smith, Paul T. Dubetz, Ernest J. Barthélemy, Alexis F. Turgeon, David Krishna Menon, Bernice G. Gulek, Mario Ganau, Halinder S. Mangat, Kathryn Hendrick, Taskeen Ullah Baber, Yashma Sherwan, Eylem Ocal, Kee B. Park, Walt D. Johnson, Franco Servadei, Gail Rosseau, Peter J. A. Hutchinson, Tariq Khan. DOI 10.3390/brainsci16020134

Transfusion thresholds and other strategies for guiding red blood cell transfusion Cochrane Database of Systematic Reviews, 2025. Jeffrey L Carson, Simon J Stanworth, Jane A Dennis, Dean A Fergusson, Monica B Pagano, Nareg H Roubinian, Alexis F Turgeon, Stacey Valentine, Marialena Trivella, Carolyn Dorée, Paul C Hébert. DOI 10.1002/14651858.CD002042.pub6

Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage New England Journal of Medicine, 2025. Shane W. English, Anthony Delaney, Dean A. Fergusson, Michaël Chassé, Alexis F. Turgeon, François Lauzier, Angie Tuttle, Ofer Sadan, Donald E. Griesdale, Gary Redekop, Martin Chapman, Mathew Hannouche, Andreas Kramer, Ian Seppelt, Andrew Udy, Demetrios J. Kutsogiannis, Ryan Zarychanski, Frédérick D’Aragon, J. Gordon Boyd, Gavin Salt, Judith Bellapart, Gordon Wood, Luis Cava, Gwynedd Pickett, Lauren Koffman, Irene Watpool, Frances Bass, Naomi Hammond, Tim Ramsay, Ranjeeta Mallick, Damon C. Scales, Christopher R. Andersen, Emily Fitzgerald, Phil Talbot, Dar Dowlatshahi, John Sinclair, Jason Acker, Shawn C. Marshall, Lauralyn McIntyre. DOI 10.1056/NEJMoa2410962

What to Measure in Aneurysmal Subarachnoid Haemorrhage Research-An International Delphi Survey TRANSLATIONAL STROKE RESEARCH, 2025. DOI 10.1007/S12975-024-01271-8

Intraperitoneal local anesthetics for postoperative pain management following intra-abdominal surgery: a systematic review and meta-analysis BMC ANESTHESIOLOGY, 2025. DOI 10.1186/S12871-025-03105-Y

Machine Learning Accurately Predicts Need for Critical Care Support in Patients Admitted to Hospital for Community-Acquired Pneumonia CRITICAL CARE EXPLORATIONS, 2025. DOI 10.1097/CCE.0000000000001262

Therapeutic-dose heparin combined with antiplatelets in noncritically ill patients with COVID-19: a secondary analysis of a multiplatform randomized controlled trial RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS, 2025. DOI 10.1016/J.RPTH.2025.102893

Liberation from mechanical ventilation using Extubation Advisor Decision Support (LEADS): protocol for a multicentre pilot trial BMJ OPEN, 2025. DOI 10.1136/BMJOPEN-2024-093853

Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial INTENSIVE CARE MEDICINE, 2025. DOI 10.1007/S00134-025-07861-W

Effect of statins on neurological functional outcomes in critically ill adult patients with traumatic brain injury: a systematic review and meta-analysis BMJ OPEN, 2025. DOI 10.1136/BMJOPEN-2024-091971

Computed Tomography Perfusion and Angiography for Death by Neurologic Criteria JAMA NEUROLOGY, 2025. DOI 10.1001/JAMANEUROL.2025.2375

Familiarity of the Surgeon-Anesthesiologist Dyad and Major Morbidity After High-Risk Elective Surgery JAMA SURGERY, 2025. DOI 10.1001/JAMASURG.2025.1386

Development and usability testing of a multifaceted intervention to reduce low-value injury care BMC HEALTH SERVICES RESEARCH, 2025. DOI 10.1186/S12913-024-12153-Y

Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19: a randomised, controlled, open-label, adaptive platform trial THORAX, 2025. DOI 10.1136/THORAX-2024-222488

Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia (vol 51, pg 665, 2025) INTENSIVE CARE MEDICINE, 2025. DOI 10.1007/S00134-025-07954-6

Elevated Blood Pressure and Culprit Aneurysm Rebleeding During the Unsecured Period of Aneurysmal Subarachnoid Hemorrhage: A Systematic Review NEUROCRITICAL CARE, 2025. DOI 10.1007/S12028-024-02138-4

Clinical Practice Guideline Recommendations on Mental Health in Trauma: A Systematic Review JAMA SURGERY, 2025. DOI 10.1001/JAMASURG.2025.2226

Rethinking Transfusion Thresholds in Traumatic Brain Injury: More Blood, Better Outcomes CRITICAL CARE MEDICINE, 2025. DOI 10.1097/CCM.0000000000006627

Starting with the End in Mind: Recommendations to Optimize Implementation of a Novel TBI Classification from the 2024 NINDS TBI Classification and Nomenclature Workshop's Knowledge to Practice Working Group JOURNAL OF NEUROTRAUMA, 2025. DOI 10.1089/NEU.2024.0576

Pain Management Strategies and Adverse Effects of Opioids in Patients with Neurotrauma with Acute and Chronic Pain NEUROTRAUMA REPORTS, 2025. DOI 10.1177/08977151251365585

Oncological outcomes of tumor ablation compared to surgical resection in early-stage hepatocellular carcinomas: a systematic review with meta-analysis HPB, 2024. Janyssa Charbonneau, Thomas Couture, Alexis Turgeon, Sarah O'Connor, Jean-François Ouellet, Jean-François Berthin Ouellet, Alexandre Brind’Amour. DOI 10.1016/j.hpb.2024.08.008

Effectiveness of dexmedetomidine on patient-centred outcomes in surgical patients: a systematic review and Bayesian meta-analysis British Journal of Anaesthesia, 2024. Michael Verret, John B.P. Le, Manoj M. Lalu, Matthew S. Jeffers, Daniel I. McIsaac, Stuart G. Nicholls, Alexis F. Turgeon, Rashi Ramchandani, Hongda Li, Brian Hutton, Fiona Zivkovic, Megan Graham, Maxime Lê, Allison Geist, Mélanie Bérubé, Katie O'Hearn, Ian Gilron, Patricia Poulin, Helena Daudt, Guillaume Martel, Jason McVicar, Husein Moloo, Dean A. Fergusson. DOI 10.1016/j.bja.2024.06.007

Perioperative Transfusion Practices in Adults Having Noncardiac Surgery TRANSFUSION MEDICINE REVIEWS, 2024. DOI 10.1016/J.TMRV.2024.150839

Association between anaesthesia-surgery team sex diversity and major morbidity BRITISH JOURNAL OF SURGERY, 2024. DOI 10.1093/BJS/ZNAE097

Quality of life and cost-effectiveness of convalescent plasma compared to standard care for hospitalized COVID-19 patients in the CONCOR-1 trial TRANSFUSION, 2024. DOI 10.1111/TRF.17777

Preclinical Studies on Mechanisms Underlying the Protective Effects of Propranolol in Traumatic Brain Injury: A Systematic Review JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024. DOI 10.1007/S11481-024-10121-1

Clinical Practice Guideline Recommendations Injury: A Systematic Review ANNALS OF EMERGENCY MEDICINE, 2024. DOI 10.1016/J.ANNEMERGMED.2023.11.012

Heparin Dose Intensity and Organ Support-Free Days in Patients Hospitalized for COVID-19 JACC-ADVANCES, 2024. DOI 10.1016/J.JACADV.2023.100780

Calcineurin Inhibitor in NEuRoloGically deceased donors to decrease kidney delayed graft function study: study protocol of the CINERGY Pilot randomised controlled trial BMJ OPEN, 2024. DOI 10.1136/BMJOPEN-2024-086777

Effectiveness of dexmedetomidine during surgery under general anaesthesia on patient-centred outcomes: a systematic review and Bayesian meta-analysis protocol BMJ OPEN, 2024. DOI 10.1136/BMJOPEN-2023-080012

Haemoglobin values, transfusion practices, and long-term outcomes in critically ill patients with traumatic brain injury: a secondary analysis of CENTER-TBI CRITICAL CARE, 2024. DOI 10.1186/S13054-024-04980-6

Intraoperative pharmacologic opioid minimisation strategies and patient-centred outcomes after surgery: a scoping review BRITISH JOURNAL OF ANAESTHESIA, 2024. DOI 10.1016/J.BJA.2024.01.006

Use of opioids and opioid alternatives during general anesthesia: a pan-Canadian survey among anesthesiologists CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2024. DOI 10.1007/S12630-024-02847-6

Complex Thrombo-Inflammatory Responses versus Outcomes of Non-COVID-19 Community-Acquired Pneumonia and COVID-19 JOURNAL OF INNATE IMMUNITY, 2024. DOI 10.1159/000542420

Shifting Balance of the Risk-Benefit of Restrictive Transfusion Strategies in Neurocritically Ill Patients-Is Less Still More? JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2024. DOI 10.1001/JAMA.2024.20416

The association of antiplatelet agents with mortality among patients with non-COVID-19 community-acquired pneumonia: a systematic review and meta-analysis RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS, 2024. DOI 10.1016/J.RPTH.2024.102526

Low-Value Clinical Practices in Pediatric Trauma Care JAMA NETWORK OPEN, 2024. DOI 10.1001/JAMANETWORKOPEN.2024.40983

Barriers, Solutions, and Opportunities for Adapting Critical Care Clinical Trials in the COVID-19 Pandemic JAMA NETWORK OPEN, 2024. DOI 10.1001/JAMANETWORKOPEN.2024.20458

Pulmonary complications and mortality among COVID-19 patients undergoing a surgery: a multicentre cohort study BMJ OPEN, 2024. DOI 10.1136/BMJOPEN-2024-090158

Tranexamic Acid During Radical Cystectomy A Randomized Clinical Trial JAMA SURGERY, 2024. DOI 10.1001/JAMASURG.2024.4183

Exploring the impact of a context-adapted decision aid and online training about shared decision making about goals of care with elderly patients in the intensive care unit: a mixed-methods study medRxiv, 2024. DOI 10.1101/2024.09.07.24313154

Blood Pressure Management in Early Aneurysmal Subarachnoid Hemorrhage: A National Cross-Sectional Survey of Canadian Intensivists and Cerebrovascular Neurosurgeons NEUROCRITICAL CARE, 2024. DOI 10.1007/S12028-024-02011-4

Frequency of Screening and Spontaneous Breathing Trial Techniques: A Randomized Clinical Trial JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2024. DOI 10.1001/JAMA.2024.20631

Community versus academic hospital community-acquired pneumonia patients: a nested cohort study PNEUMONIA, 2024. DOI 10.1186/S41479-024-00143-X

CODA: an open-source platform for federated analysis and machine learning on distributed healthcare data JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 2024. DOI 10.1093/JAMIA/OCAD235

Effects of Losartan on Patients Hospitalized for Acute Coronavirus Disease 2019: A Randomized Controlled Trial CLINICAL INFECTIOUS DISEASES, 2024. DOI 10.1093/CID/CIAE306

Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury NEW ENGLAND JOURNAL OF MEDICINE, 2024. DOI 10.1056/NEJMOA2404360

Implementation of an audit and feedback module targeting low-value clinical practices in a provincial trauma quality assurance program: a cost-effectiveness study BMC HEALTH SERVICES RESEARCH, 2024. DOI 10.1186/S12913-024-10969-2

The Association Between Familiarity of the Surgeon-Anesthesiologist Dyad and Post-Operative Patient Outcomes for Complex Gastrointestinal Cancer Surgery: A Population-Based Study ANNALS OF SURGICAL ONCOLOGY, 2023.

Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2023. DOI 10.1001/JAMA.2023.21407

The Efficacy of Glutamine Supplementation in Severe Adult Burn Patients: A Systematic Review With Trial Sequential Meta-Analysis CRITICAL CARE MEDICINE, 2023. DOI 10.1097/CCM.0000000000005887

Evaluating the effectiveness of a multifaceted intervention to reduce low-value care in adults hospitalized following trauma: a protocol for a pragmatic cluster randomized controlled trial IMPLEMENTATION SCIENCE, 2023. DOI 10.1186/S13012-023-01279-Y

Clinical Practice Guideline Recommendations in Pediatric Orthopaedic Injury: A Systematic Review JOURNAL OF PEDIATRIC ORTHOPAEDICS, 2023. DOI 10.1097/BPO.0000000000002496

Good or best practice statements: proposal for the operationalisation and implementation of GRADE guidance BMJ EVIDENCE-BASED MEDICINE, 2023. DOI 10.1136/BMJEBM-2022-111962

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2023. DOI 10.1001/JAMA.2022.23257

Association Between Familiarity of the Surgeon-Anesthesiologist Dyad and Postoperative Patient Outcomes for Complex Gastrointestinal Cancer Surgery (vol 158, pg 465, 2023) JAMA SURGERY, 2023. DOI 10.1001/JAMASURG.2023.0958

Frequency of screening and SBT Technique Trial-North American Weaning Collaboration (FAST-NAWC): an update to the protocol and statistical analysis plan TRIALS, 2023. DOI 10.1186/S13063-023-07079-5

Engaging patients in anesthesiology research: a rewarding frontier CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2023. DOI 10.1007/S12630-023-02432-3

Tracheostomy <i>versus</i> prolonged intubation in moderate to severe traumatic brain injury: a multicentre retrospective cohort study CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2023. DOI 10.1007/S12630-023-02539-7

Clinical practice guideline recommendations for pediatric solid organ injury care: A Systematic Review JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2023. DOI 10.1097/TA.0000000000004015

Equity issues rarely addressed in the development of COVID-19 formal recommendations and good practice statements: a cross-sectional study JOURNAL OF CLINICAL EPIDEMIOLOGY, 2023. DOI 10.1016/J.JCLINEPI.2023.08.002

Potential Avoidable Costs of Low-Value Clinical Practices in Acute Injury Care in an Integrated Canadian Provincial Trauma System JAMA SURGERY, 2023. DOI 10.1001/JAMASURG.2023.2510

Anemia and Red Blood Cell Transfusion in Aneurysmal Subarachnoid Hemorrhage NEUROCRITICAL CARE, 2023. DOI 10.1007/S12028-023-01815-0

Calcineurin Inhibition in Deceased Organ Donors: A Systematic Review and Meta-analysis of Preclinical Studies TRANSPLANTATION DIRECT, 2023. DOI 10.1097/TXD.0000000000001519

Simvastatin in Critically Ill Patients with Covid-19 NEW ENGLAND JOURNAL OF MEDICINE, 2023. DOI 10.1056/NEJMOA2309995

Real-World Effectiveness of Nirmatrelvir/Ritonavir on Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Prevention: A Population-based Cohort Study in the Province of Quebec, Canada CLINICAL INFECTIOUS DISEASES, 2023. DOI 10.1093/CID/CIAD287

Isolated Brainstem Death is Rare and is Associated with Infratentorial Stroke Among Patients Suspected of Death by Neurologic Criteria NEUROLOGY, 2023. DOI 10.1212/WNL.0000000000201744

Association Between Familiarity of the Surgeon-Anesthesiologist Dyad and Postoperative Patient Outcomes for Complex Gastrointestinal Cancer Surgery JAMA SURGERY, 2023. DOI 10.1001/JAMASURG.2022.8228

Association of age with death and withdrawal of life-sustaining therapy after severe traumatic brain injury CANADIAN JOURNAL OF SURGERY, 2023. DOI 10.1503/CJS.013721

Variation in Anesthesiology Provider-Volume for Complex Gastrointestinal Cancer Surgery A Population-Based Study ANNALS OF SURGERY, 2023. DOI 10.1097/SLA.0000000000005811

Patient Relevance of the Modified Rankin Scale in Subarachnoid Hemorrhage Research An International Cross-sectional Survey NEUROLOGY, 2023. DOI 10.1212/WNL.0000000000206879

Evaluating variation in perioperative red blood cell transfusion for patients undergoing elective gastrointestinal cancer surgery SURGERY, 2023. DOI 10.1016/J.SURG.2022.09.014

Diagnostic accuracy of ancillary tests for death by neurologic criteria: a systematic review and meta-analysis CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2023. DOI 10.1007/S12630-023-02426-1

Interdisciplinary strategies to prevent long-term and detrimental opioid use following trauma: a stakeholder consensus study PAIN MEDICINE, 2023. DOI 10.1093/PM/PNAD037

Pediatric vs Adult or Mixed Trauma Centers in Children Admitted to Hospitals Following Trauma A Systematic Review and Meta-Analysis JAMA NETWORK OPEN, 2023. DOI 10.1001/JAMANETWORKOPEN.2023.34266

Pediatric Moderate and Severe Traumatic Brain Injury: A Systematic Review of Clinical Practice Guideline Recommendations JOURNAL OF NEUROTRAUMA, 2023. DOI 10.1089/NEU.2023.0149

Strategies to prevent long-term opioid use following trauma: a Canadian practice survey CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2023. DOI 10.1007/S12630-022-02328-8

Clinical Outcomes of Indigenous Versus Non-Indigenous Patients: A Multicenter Retrospective Cohort Study in the Province of Quebec JOURNAL OF PRIMARY CARE AND COMMUNITY HEALTH, 2023. DOI 10.1177/21501319231178654

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19 A Randomized Clinical Trial JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2023. DOI 10.1001/JAMA.2023.4480

Effect of Taste Additives on the Palatability of Activated Charcoal: a Systematic Review JOURNAL OF MEDICAL TOXICOLOGY, 2023. DOI 10.1007/S13181-023-00934-6

Intraoperative pharmacologic opioid minimisation strategies and patient-centred outcomes after surgery: a scoping review protocol BMJ OPEN, 2023. DOI 10.1136/BMJOPEN-2022-070748

The Association Between Hospital High-volume Anesthesiology Care and Patient Outcomes for Complex Gastrointestinal Cancer Surgery A Population-based Study ANNALS OF SURGERY, 2023. DOI 10.1097/SLA.0000000000005738

Impact of Early Tracheostomy Versus Late or No Tracheostomy in Nonneurologically Injured Adult Patients: A Systematic Review and Meta-Analysis* CRITICAL CARE MEDICINE, 2023. DOI 10.1097/CCM.0000000000005699

Near Infrared Spectroscopy for Poor Grade Aneurysmal Subarachnoid Hemorrhage-A Concise Review FRONTIERS IN NEUROLOGY, 2022. DOI 10.3389/FNEUR.2022.874393

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial (vol 27, pg 2012, 2021) NATURE MEDICINE, 2022. DOI 10.1038/S41591-021-01667-1

White blood cell count trajectory and mortality in septic shock: a historical cohort study CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2022. DOI 10.1007/S12630-022-02282-5

Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol BMJ OPEN, 2022. DOI 10.1136/BMJOPEN-2022-067117

Remdesivir in patients hospitalized with COVID-19 in Canada: A randomized, controlled clinical trial CANADIAN MEDICAL ASSOCIATION JOURNAL, 2022. DOI 10.1503/CMAJ.211698-F

Management of Rhabdomyolysis in a Patient Treated with Clozapine: A Case Report and Clinical Recommendations CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE, 2022. DOI 10.9758/CPN.2022.20.1.194

A taxonomy and framework for identifying and developing actionable statements in guidelines suggests avoiding informal recommendations JOURNAL OF CLINICAL EPIDEMIOLOGY, 2022. DOI 10.1016/J.JCLINEPI.2021.09.028

Clinical evaluation and ancillary testing for the diagnosis of death by neurologic criteria: a cross-sectional survey of Canadian intensivists CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2022. DOI 10.1007/S12630-021-02166-0

Economic evaluations of audit and feedback interventions: a systematic review BMJ QUALITY & SAFETY, 2022. DOI 10.1136/BMJQS-2022-014727

Traumatic brain injury: progress and challenges in prevention, clinical care, and research LANCET NEUROLOGY, 2022. DOI 10.1016/S1474-4422(22)00309-X

Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial CANADIAN MEDICAL ASSOCIATION JOURNAL, 2022. DOI 10.1503/CMAJ.211698

Effect of Intermittent Pneumatic Compression in Addition to Pharmacologic Prophylaxis for Thromboprophylaxis in Hospitalized Adult Patients: A Systematic Review and Meta-Analysis CRITICAL CARE EXPLORATIONS, 2022. DOI 10.1097/CCE.0000000000000769

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2022. DOI 10.1001/JAMA.2022.2910

A Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries NEW ENGLAND JOURNAL OF MEDICINE, 2022. DOI 10.1056/NEJMOA2203364

Interhospital Variations in Resource Use Intensity for In-hospital Injury Deaths A Retrospective Multicenter Cohort Study ANNALS OF SURGERY, 2022. DOI 10.1097/SLA.0000000000003922

Validation of Quality Indicators Targeting Low-Value Trauma Care JAMA SURGERY, 2022. DOI 10.1001/JAMASURG.2022.3912

Quality Indicators Targeting Low-Value Clinical Practices in Trauma Care JAMA SURGERY, 2022. DOI 10.1001/JAMASURG.2022.0812

Clinical practice guideline recommendations for pediatric injury care: protocol for a systematic review BMJ OPEN, 2022. DOI 10.1136/BMJOPEN-2021-060054

An evaluation of the COVID-19 recommendation map identified diverging clinical and public health guidance JOURNAL OF CLINICAL EPIDEMIOLOGY, 2022. DOI 10.1016/J.JCLINEPI.2022.03.008

Economic Evaluation of In-Hospital Clinical Practices in Acute Injury Care: A Systematic Review VALUE IN HEALTH, 2022. DOI 10.1016/J.JVAL.2021.10.018

Prioritization of indicators of the quality of care provided to older adults with frailty by key stakeholders from five canadian provinces BMC GERIATRICS, 2022. DOI 10.1186/S12877-022-02843-9

Strategies aimed at preventing long-term opioid use in trauma and orthopaedic surgery: a scoping review BMC MUSCULOSKELETAL DISORDERS, 2022. DOI 10.1186/S12891-022-05044-Y

Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit NEW ENGLAND JOURNAL OF MEDICINE, 2022. DOI 10.1056/NEJMOA2200644

Which actionable statements qualify as good practice statements In Covid-19 guidelines? A systematic appraisal BMJ EVIDENCE-BASED MEDICINE, 2022. DOI 10.1136/BMJEBM-2021-111866

Intensity of hospital resource use following traumatic brain injury: a multicentre cohort study, 2013-2016 CANADIAN JOURNAL OF SURGERY, 2022. DOI 10.1503/CJS.007819

Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial INTENSIVE CARE MEDICINE, 2021. DOI 10.1007/S00134-021-06448-5

Variation in prophylactic tranexamic acid administration among anesthesiologists and surgeons in orthopedic surgery: a retrospective cohort study CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2021. DOI 10.1007/S12630-021-01939-X

Association of perioperative red blood cell transfusions with all-cause and cancer-specific death in patients undergoing surgery for gastrointestinal cancer JOURNAL OF CLINICAL ONCOLOGY, 2021. DOI 10.1200/JCO.2021.39.3_SUPPL.464

Intravenous immune globulin in septic shock: a Canadian national survey of critical care medicine and infectious disease specialist physicians (Feb, 10.1007/s12630-021-01941-3, 2021) CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2021. DOI 10.1007/S12630-021-01964-W

Declining Use of Red Blood Cell Transfusions for Gastrointestinal Cancer Surgery: A Population-Based Analysis ANNALS OF SURGICAL ONCOLOGY, 2021. DOI 10.1245/S10434-020-09291-Y

Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2021. DOI 10.1016/J.JTCVS.2021.03.091

Evaluation of Transfusion Practices in Noncardiac Surgeries at High Risk for Red Blood Cell Transfusion: A Retrospective Cohort Study TRANSFUSION MEDICINE REVIEWS, 2021. DOI 10.1016/J.TMRV.2020.08.001

Intravenous immune globulin in septic shock: a Canadian national survey of critical care medicine and infectious disease specialist physicians CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2021. DOI 10.1007/S12630-021-01941-3

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 – Preliminary report medRxiv, 2021. DOI 10.1101/2021.01.07.21249390

Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score BJS-BRITISH JOURNAL OF SURGERY, 2021. DOI 10.1093/BJS/ZNAB183

Prophylactic tranexamic acid use in non-cardiac surgeries at high risk for transfusion TRANSFUSION MEDICINE, 2021. DOI 10.1111/TME.12780

Association of perioperative red blood cell transfusions with all-cause and cancer-specific death in patients undergoing surgery for gastrointestinal cancer: Long-term outcomes from a population-based cohort SURGERY, 2021. DOI 10.1016/J.SURG.2021.02.003

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 NEW ENGLAND JOURNAL OF MEDICINE, 2021. DOI 10.1056/NEJMOA2103417

Association Between Anesthesiologist Volume and Short-term Outcomes in Complex Gastrointestinal Cancer Surgery JAMA SURGERY, 2021. DOI 10.1001/JAMASURG.2021.0135

The Biobanque quebecoise de la COVID-19 (BQC19)-A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories PLOS ONE, 2021. DOI 10.1371/JOURNAL.PONE.0245031

Impact of Bacillus Calmette-Guerin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infection BJS OPEN, 2021. DOI 10.1093/BJSOPEN/ZRAB131

Transfusion in orthopaedic surgery A RETROSPECTIVE MULTICENTRE COHORT STUDY BONE & JOINT OPEN, 2021. DOI 10.1302/2633-1462.210.BJO-2021-0077.R1

Gabapentinoids: When Is the Right Moment to Stop? ANESTHESIA AND ANALGESIA, 2021. DOI 10.1213/ANE.0000000000005727

Epidemiology of intravenous immune globulin in septic shock: a retrospective cohort analysis of the Premier Healthcare Database CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2021. DOI 10.1007/S12630-021-02081-4

Convalescent plasma for hospitalized patients with COVID-19 and the effect of plasma antibodies: a randomized controlled, open-label trial medRxiv, 2021. DOI 10.1101/2021.06.29.21259427

THE CONTRIBUTION OF SURGEON AND HOSPITAL VARIATION IN TRANSFUSION PRACTICE TO OUTCOMES FOR PATIENTS UNDERGOING GASTROINTESTINAL CANCER SURGERY: A POPULATION-BASED ANALYSIS GASTROENTEROLOGY, 2021.

Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 NEW ENGLAND JOURNAL OF MEDICINE, 2021. DOI 10.1056/NEJMOA2105911

Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials BMC INFECTIOUS DISEASES, 2021. DOI 10.1186/S12879-021-06829-7

Low-value injury admissions in an integrated Canadian trauma system: A multicentre cohort study INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2021. DOI 10.1111/IJCP.14473

Trauma 2021 Trauma Association of Canada Annual Scientific Meeting, Vancouver, British Columbia (virtual), April 12-16, 2021 CANADIAN JOURNAL OF SURGERY, 2021. DOI 10.1503/CJS.014121

Cerebral Hemodynamics and Intracranial Compliance Impairment in Critically Ill COVID-19 Patients: A Pilot Study BRAIN SCIENCES, 2021. DOI 10.3390/BRAINSCI11070874

Red blood cell transfusion in animal models of acute brain injuries: a systematic review protocol SYSTEMATIC REVIEWS, 2021. DOI 10.1186/S13643-021-01703-8

Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study BMC ANESTHESIOLOGY, 2021. DOI 10.1186/S12871-021-01233-9

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial NATURE MEDICINE, 2021. DOI 10.1038/S41591-021-01488-2

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 NEW ENGLAND JOURNAL OF MEDICINE, 2021. DOI 10.1056/NEJMOA2100433

Evaluating Variation in Perioperative Red Blood Cell Transfusion for Patients Undergoing Elective Gastrointestinal Cancer Surgery: A Population-based Analysis JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2021.

Adherence to Clinical Practice Guideline Recommendations on Low-Value Injury Care: A Multicenter Retrospective Cohort Study VALUE IN HEALTH, 2021. DOI 10.1016/J.JVAL.2021.06.008

Development and Validation of a Hospital Indicator of Activity-Based Costs for Injury Admissions VALUE IN HEALTH, 2021. DOI 10.1016/J.JVAL.2020.11.011

Evaluation of Intensive vs Standard Blood Pressure Reduction and Association With Cognitive Decline and Dementia A Systematic Review and Meta-analysis JAMA NETWORK OPEN, 2021. DOI 10.1001/JAMANETWORKOPEN.2021.34553

Use of activated charcoal for decontamination in 0 to 5-year-olds presenting to the emergency department with poisoning CLINICAL TOXICOLOGY, 2021.

Sensitivity of Ancillary Testing in Brain Death/Death by Neurological Criteria: A Systematic Review and Meta-analysis NEUROLOGY, 2021.

Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2021. DOI 10.1001/JAMA.2021.18178

Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): updates study protocol for an international, multicentre, randomized, open-label trial TRIALS, 2021. DOI 10.1186/S13063-021-05235-3

Validity and reliability of the poisoning severity score in a pediatric poisoned population CLINICAL TOXICOLOGY, 2021.

Prognostic Research in Traumatic Brain Injury: Markers, Modeling, and Methodological Principles JOURNAL OF NEUROTRAUMA, 2021. DOI 10.1089/NEU.2019.6708

Effect of Yttrium-90 transarterial radioembolization in patients with non-surgical hepatocellular carcinoma: A systematic review and meta-analysis PLOS ONE, 2021. DOI 10.1371/JOURNAL.PONE.0247958

Validation of the modified NUTrition Risk Score (mNUTRIC) in mechanically ventilated, severe burn patients: A prospective multinational cohort study BURNS, 2021. DOI 10.1016/J.BURNS.2021.05.010

Perioperative Use of Gabapentinoids: Reply ANESTHESIOLOGY, 2021. DOI 10.1097/ALN.0000000000003667