André Tchernof

• Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (Affilié à l’Université Laval)
• Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (Reconnu FRQ - secteur santé)
• Institut sur la nutrition et les aliments fonctionnels

Financements des 2 dernières années

• Alan Ramalho, Doctorat en nutrition
• Amélie Lachance, Doctorat en nutrition
• Eve-Julie Tremblay, Doctorat en nutrition
• Félix Marcotte, Maîtrise en nutrition - avec mémoire
• Tristan Rocheleau, Doctorat en sciences cliniques et biomédicales

Encadrements des 5 dernières années

• Amélie Lachance, Maîtrise en nutrition - avec mémoire
• Emilie Bernier, Maîtrise en nutrition - avec mémoire
• Fanny Lajeunesse-Trempe, Doctorat en nutrition
• Giada Ostinelli, Doctorat en nutrition
• Luis Fernando Sorroza Martinez, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Marianne Côté, Maîtrise en nutrition - avec mémoire

Travaux de recherche des 5 dernières années

Changes in food reward are associated with improvements in metabolic markers and eating behaviors after bariatric surgery Physiology & Behavior, 2027. Amélie Lachance, Victoria Toro, Marianne Legault, Patrick Gagnon, Mélissa Pelletier, Laurent Biertho, Véronique Provencher, Sylvain Iceta, André Tchernof, Frédéric Picard, Andréanne Michaud. DOI 10.1016/j.physbeh.2026.115518

Adults with Obesity and Hyperglycemia have Higher Arachidonic and Docosahexaenoic Acid in Subcutaneous Adipose Tissue Journal of Lipid Research, 2026. Sabrina Ziai, Mihir Parikh, Narjes Mosavari, Ruxandra D. Rotarescu, Chuck T. Chen, Richard P. Bazinet, André Tchernof, Anthony J. Hanley, Adam H. Metherel, Jacqueline L. Beaudry. DOI 10.1016/j.jlr.2026.101106

Mammary Adipocyte Size, Obesity-Related Breast Adipose Tissue Dysfunction, and Breast Cancer: A Systematic Review and Meta-Analysis Cancers, 2026. Ouafa Badre, Sue-Ling Chang, Belkacem Abdous, Julie Lemieux, Francine Durocher, André Tchernof, Caroline Diorio. DOI 10.3390/cancers18152464

A longitudinal investigation of eating behavior, attention-deficit/hyperactivity disorder, and weight loss outcomes following bariatric surgery Surgery for Obesity and Related Diseases, 2026. Mathilde Yergeau, Justine Daoust, Maxime Legendre, Mélissa Pelletier, Laurent Biertho, André Tchernof, Andréanne Michaud, Catherine Bégin. DOI 10.1016/j.soard.2026.07.011

Agnostic polygenic prediction of weight loss after bariatric surgery JCI Insight, 2026. Bastien Vallée Marcotte, Juan de Toro-Martín, André Tchernof, Louis Pérusse, Simon Marceau, Marie-Claude Vohl. DOI 10.1172/jci.insight.198133

Pharmacokinetics of cefazolin in bariatric surgery patients: a preoperative perspective Journal of Antimicrobial Chemotherapy, 2026. Alexandra Porlier, Mélanie Nadeau, Jérôme Laflamme, Sylvie Pilote, Philippe Gervais, Benoit Drolet, André Tchernof, Laurent Biertho, Simon Marceau, Chantale Simard, François Julien. DOI 10.1093/jac/dkag150

Impact of AKR1C2 and AKR1C3 single-nucleotide polymorphism rs28571848 in adipose tissues of individuals with severe obesity American Journal of Physiology-Endocrinology and Metabolism, 2026. Giada Ostinelli, Alan Ramalho, Marie-Fréderique Gauthier, François Julien, Laurent Biertho, Marie-Claude Vohl, André Tchernof. DOI 10.1152/ajpendo.00512.2024

Changes in food reward are associated with improvements in metabolic markers and eating behaviors after bariatric surgery 2026. Amélie Lachance, Victoria Toro, Marianne Legault, Patrick Gagnon, Mélissa Pelletier, Laurent Biertho, Véronique Provencher, Sylvain Iceta, André Tchernof, Frédéric Picard, Andréanne Michaud. DOI 10.2139/ssrn.7119527

High-throughput measurement of adipocyte size with open-source software using whole-slide adipose tissue images Adipocyte, 2025. Alan Ramalho, Marie-Frédérique Gauthier, Ina Maltais-Payette, Giada Ostinelli, Frédéric Hould, Laurent Biertho, André Tchernof. DOI 10.1080/21623945.2025.2528437

Circulating Amino Acid Changes Three Years After Bariatric Surgery Metabolites, 2025. Ina Maltais-Payette, Fannie Lajeunesse-Trempe, Mélanie Nadeau, Léonie Bouvet-Bouchard, Frédéric Simon Hould, Laurent Biertho, André Tchernof. DOI 10.3390/metabo15050297

Magnetic duodenoileal anastomosis with sleeve gastrectomy: a prospective multicenter study Surgery for Obesity and Related Diseases, 2025. Laurent Biertho, Simon Marceau, Mélanie Nadeau, Stéfane Lebel, François Julien, André Tchernof, Thomas Ransom, Richard T. Spence, James Ellesmere. DOI 10.1016/j.soard.2024.10.020

Anthropometric Indices and Metabolic Dysfunction–Associated Fatty Liver Disease in Males and Females Living With Severe Obesity Canadian Journal of Gastroenterology and Hepatology, 2025. Fannie Lajeunesse-Trempe, Selena Dugas, Ina Maltais-Payette, Ève-Julie Tremblay, Marie-Eve Piché, Georgios K. Dimitriadis, Annie Lafortune, Simon Marceau, Laurent Biertho, André Tchernof. DOI 10.1155/cjgh/5545227

Origin of dedifferentiated adipocyte-derived cells (DFAT) during ceiling culture in an Adiponectin Cre-Recombinase mouse model Biochemistry and Cell Biology, 2025. Marie-Frédérique Gauthier, Giada Ostinelli, Mélissa Pelletier, André Tchernof. DOI 10.1139/bcb-2024-0140

Rise in plasma bile acids following hypoabsorptive bariatric surgeries predicts beneficial metabolic and homeostatic outcomes in male rats American Journal of Physiology-Gastrointestinal and Liver Physiology, 2024. Paulette Mukorako, Audrey-Anne Lavoie, Jocelyn Trottier, Natacha Lemoine, Laurent Biertho, Stéfane Lebel, Julie Plamondon, André Tchernof, David H. St-Pierre, André Marette, Olivier Barbier, Denis Richard. DOI 10.1152/ajpgi.00289.2023

Resistance training and cardiometabolic risk in women with metabolically healthy and unhealthy obesity Applied Physiology, Nutrition, and Metabolism, 2024. Eve-Julie Tremblay, Paul Peyrel, Antony D. Karelis, Rémi Rabasa-Lhoret, André Tchernof, Denis R. Joanisse, Pascale Mauriège. DOI 10.1139/apnm-2023-0279

Genetic assessment of efficacy and safety profiles of coagulation cascade proteins identifies Factors II and XI as actionable anticoagulant targets European Heart Journal Open, 2024. Eloi Gagnon, Arnaud Girard, Jérôme Bourgault, Erik Abner, Dipender Gill, Sébastien Thériault, Marie-Claude Vohl, André Tchernof, Tõnu Esko, Patrick Mathieu, Benoit J Arsenault. DOI 10.1093/ehjopen/oeae043

Adiposity Phenotypes and Associated Cardiometabolic Risk Profile in the Inuit Population of Nunavik Nutrients, 2024. Fannie Lajeunesse-Trempe, Marie-Eve Piché, Paul Poirier, André Tchernof, Pierre Ayotte. DOI 10.3390/nu16050725

Genetic assessment of efficacy and safety profiles of coagulation cascade proteins identifies Factors II and XI as actionable anticoagulant targets 2023. Eloi Gagnon, Arnaud Girard, Jérôme Bourgault, Erik Abner, Dipender Gill, Sébastien Thériault, Marie-Claude Vohl, André Tchernof, Tõnu Esko, Patrick Mathieu, Benoit J. Arsenault. DOI 10.1101/2023.12.05.23299567

17β‐hydroxysteroid dehydrogenase type 2 activity, expression and cellular localization in abdominal adipose tissues from women Clinical Endocrinology, 2023. Mohamed Fouad Mansour, Sophie Blanchette, Mélissa Pelletier, Donald Poirier, André Tchernof. DOI 10.1111/cen.14838

Impact of weight loss on brain age: Improved brain health following bariatric surgery NeuroImage, 2022. Yashar Zeighami, Mahsa Dadar, Justine Daoust, Mélissa Pelletier, Laurent Biertho, Léonie Bouvet-Bouchard, Stephanie Fulton, André Tchernof, Alain Dagher, Denis Richard, Alan Evans, Andréanne Michaud. DOI 10.1016/j.neuroimage.2022.119415

Acceptability and Feasibility of the Telehealth Bariatric Behavioral Intervention to Increase Physical Activity: Protocol for a Single-Case Experimental Study JMIR Research Protocols, 2022. Aurélie Baillot, Maxime St-Pierre, Josyanne Lapointe, Paquito Bernard, Dale Bond, Ahmed Jérôme Romain, Pierre Y Garneau, Laurent Biertho, André Tchernof, Patricia Blackburn, Marie-France Langlois, Jennifer Brunet. DOI 10.2196/39633

Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity Amino Acids, 2022. Ina Maltais-Payette, Jinchu Vijay, Marie-Michelle Simon, Jacques Corbeil, Francis Brière, Elin Grundberg, André Tchernof. DOI 10.1007/s00726-022-03181-1

Adipocyte Hypertrophy Associates With Differential <i>in vivo</i> Postprandial Fatty Acid Metabolism, Adipose Single-Cell Landscape and Transcriptional Dynamics 2022. Run Zhou Ye, Emilie Montastier, Frédérique Frisch, Christophe Noll, Hugues Allard-Chamard, Nicolas Gévry, André Tchernof, André C. Carpentier. DOI 10.2139/ssrn.4231652

Revisional Surgery: Second-Stage Duodenal Switch Laparoscopic Sleeve Gastrectomy, 2021. Laurent Biertho, Simon Marceau, Stéfane Lebel, François Julien, André Tchernof. DOI 10.1007/978-3-030-57373-7_55

Association between visceral adiposity index, binge eating behavior, and grey matter density in caudal anterior cingulate cortex in severe obesity Brain Sciences, 2021. Iceta, S., Dadar, M., Daoust, J., Scovronec, A., Leblanc, V., Pelletier, M., Biertho, L., Tchernof, A., Bégin, C., Michaud, A.. DOI 10.3390/brainsci11091158

Deciphering the Association Between Hypothalamus-Pituitary-Adrenal Axis Activity and Obesity: A Meta-Analysis Obesity, 2021. Ostinelli, G., Scovronec, A., Iceta, S., Ouellette, A.-S., Lemieux, S., Biertho, L., Bégin, C., Michaud, A., Tchernof, A.. DOI 10.1002/oby.23125

Consistent gut bacterial and short-chain fatty acid signatures in hypoabsorptive bariatric surgeries correlate with metabolic benefits in rats International Journal of Obesity, 2021. Mukorako, P., Lemoine, N., Biertho, L., Lebel, S., Roy, M.-C., Plamondon, J., Tchernof, A., Varin, T.V., Anhê, F.F., St-Pierre, D.H., Marette, A., Richard, D.. DOI 10.1038/s41366-021-00973-5

Bacterial postbiotics as promising tools to mitigate cardiometabolic diseases Journal of Lipid and Atherosclerosis, 2021. Anhê, F.F., Jensen, B.A.H., Perazza, L.R., Tchernof, A., Schertzer, J.D., Marette, A.. DOI 10.12997/jla.2021.10.2.123

Spontaneous neural activity changes after bariatric surgery: A resting-state fMRI study NeuroImage, 2021. Zeighami, Y., Iceta, S., Dadar, M., Pelletier, M., Nadeau, M., Biertho, L., Lafortune, A., Tchernof, A., Fulton, S., Evans, A., Richard, D., Dagher, A., Michaud, A.. DOI 10.1016/j.neuroimage.2021.118419

Associations between markers of mammary adipose tissue dysfunction and breast cancer prognostic factors International Journal of Obesity, 2021. Laforest, S., Ennour-Idrissi, K., Ouellette, G., Gauthier, M.-F., Michaud, A., Durocher, F., Tchernof, A., Diorio, C.. DOI 10.1038/s41366-020-00676-3

AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants Molecular and Cellular Endocrinology, 2021. Ostinelli, G., Vijay, J., Vohl, M.-C., Grundberg, E., Tchernof, A.. DOI 10.1016/j.mce.2021.111220

Management of Obesity in Cardiovascular Practice: JACC Focus Seminar Journal of the American College of Cardiology, 2021. Després, J.-P., Carpentier, A.C., Tchernof, A., Neeland, I.J., Poirier, P.. DOI 10.1016/j.jacc.2021.05.035

Associations of Biomarkers of Inflammation and Breast Cancer in the Breast Adipose Tissue of Women with Combined Measures of Adiposity Journal of Obesity, 2021. Chang, S.-L., Tchernof, A., Durocher, F., Diorio, C.. DOI 10.1155/2021/3620147

Liver enhancer signature and regulatory network of non-alcoholic steatohepatitis resistance in humans with obesity bioRxiv, 2021. Hung, Y.-H., Sritharan, R., Vohl, M.-C., Ilkayeva, O., Biertho, L., Tchernof, A., White, P.J., Sethupathy, P.. DOI 10.1101/2021.08.20.457162

IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery Cell Reports Medicine, 2021. Faramia, J., Hao, Z., Mumphrey, M.B., Townsend, R.L., Miard, S., Carreau, A.-M., Nadeau, M., Frisch, F., Baraboi, E.-D., Grenier-Larouche, T., Noll, C., Li, M., Biertho, L., Marceau, S., Hould, F.-S., Lebel, S., Morrison, C.D., Münzberg, H., Richard, D., Carpentier, A.C., Tchernof, A., Berthoud, H.-R., Picard, F.. DOI 10.1016/j.xcrm.2021.100248