Ismail Fliss

• Centre de recherche en infectiologie
• Centre de recherche en sciences et technologie du lait
• Institut sur la nutrition et les aliments fonctionnels

Financements des 2 dernières années

• Abouzar Ghasemi, Doctorat en sciences des aliments - microbiologie alimentaire
• Amal Mamjoud, Stage postdoctoral en microbiologie alimentaire
• Angélique Salandre, Doctorat en sciences des aliments - microbiologie alimentaire
• Farzad Mohammadi, Stage postdoctoral en microbiologie alimentaire
• Forough Yaghoubi, Doctorat en sciences des aliments - microbiologie alimentaire
• James Kamen Ngotom, Doctorat en sciences des aliments - microbiologie alimentaire
• Rihab Ben Abdallah, Doctorat en sciences des aliments
• Rosie Beaulieu, Doctorat en sciences des aliments - microbiologie alimentaire
• Rosie Beaulieu, Maîtrise en sciences des aliments - microbiologie alimentaire - avec mémoire
• Samaneh Shaghaghian, Doctorat en sciences des aliments - microbiologie alimentaire
• Vahideh Vahdatmanesh, Stage postdoctoral en microbiologie alimentaire

Encadrements des 5 dernières années

• Alexandre Rulence, Doctorat en sciences des aliments
• Alexandre Rulence, Stage postdoctoral en sciences et technologie des aliments
• Amadou Ndiaye, Doctorat en sciences des aliments
• Amal Mamjoud, Doctorat en sciences des aliments - microbiologie alimentaire
• Aurore Cournoyer, Doctorat en sciences des aliments
• Charlotte Marie Roupie, Stage postdoctoral en sciences et technologie des aliments
• Farah Ajej, Maîtrise en sciences des aliments - avec mémoire
• Gautier Decabooter, Doctorat en sciences des aliments
• Khaled Abdallah, Doctorat en sciences des aliments - microbiologie alimentaire
• Liya Zhang, Stage postdoctoral en sciences et technologie des aliments
• Louis-David Guay, Doctorat en sciences pharmaceutiques
• Mahsa Rezaee, Stage postdoctoral en sciences et technologie des aliments
• Marianne Levasseur, Maîtrise en sciences des aliments - avec mémoire
• Mariem Amri, Maîtrise en sciences des aliments - avec mémoire
• Md Ramim Tanver Rahman, Doctorat en sciences pharmaceutiques
• Md Saifur Rahman, Stage postdoctoral en sciences et technologie des aliments
• Nissa Niboucha, Maîtrise en sciences des aliments - microbiologie alimentaire - avec mémoire
• Nissa Niboucha, Doctorat en sciences des aliments - microbiologie alimentaire
• Samira Soltani, Stage postdoctoral en sciences et technologie des aliments
• Samuel Cashman-Kadri, Doctorat en sciences des aliments
• Sara García Vela, Doctorat en sciences des aliments
• Soufiane Telhig, Doctorat en sciences des aliments - microbiologie alimentaire
• Takoua Yakoubi, Maîtrise en sciences des aliments - avec mémoire
• Vahideh Vahdatmanesh, Doctorat en sciences des aliments - microbiologie alimentaire
• Yasmine Lamri, Maîtrise en sciences des aliments - avec mémoire

Travaux de recherche des 5 dernières années

Investigating dietary microRNA stability and function using a transgenic milk model with unique microRNA sequences 2026. Zeinab Husseini, Nathalie Majeau, Ismail Fliss, Abderrahim Benmoussa. DOI 10.64898/2026.04.13.718217

Prevention of Staphylococcus aureus biofilm formation on catheters, contact lenses, and contact lens cases by a synthetic analogue of the antimicrobial lipopeptide humimycin Biofouling, 2026. Md Ramim Tanver Rahman, Ismail Fliss, Eric Biron. DOI 10.1080/08927014.2026.2621190

Harnessing Native Bacteria for Fermentation-Driven Valorization of Fruit By-Products into Functional Supplements 2026. ABOUZAR GHASEMI, Salwa Karboune, Denis Groleau, Ismail Fliss. DOI 10.2139/ssrn.7460134

Antimicrobial activity of electro-activated solutions produced from lactate and propionate anions against Bacillus cereus ATCC 14579 and its spores and their application in cooked rice 2026. James Kamen Ngotom, Ismail Fliss, Mohammed Aider. DOI 10.2139/ssrn.6497852

Pilot plant extraction of oligo/polysaccharides from Sidestream cranberry pomace and assessment of their techno-functional properties 2026. Rasha Aleed, Najla Ben Akacha, Amanda Waglay, Farnaz Jozedaemi, Ismail Fliss, Salwa Karboune. DOI 10.2139/ssrn.6458482

Fermentation‐Assisted Valorization: A Sustainable Strategy for Turning Fruit By‐Products Into Value‐Added Food Supplements Food Frontiers, 2026. Abouzar Ghasemi, Salwa Karboune, Denis Groleau, Ismail Fliss. DOI 10.1002/fft2.70099

Enhanced Agar Well Diffusion Method for Screening Enzyme-Producing Microorganisms 2026. ABOUZAR GHASEMI, Salwa Karboune, Denis Groleau, Ismail Fliss. DOI 10.2139/ssrn.7329673

Antibacterial and Antibiofilm Activities of Electro-Activated Solutions Generated from Lactate and Propionate Anions against Pseudomonas fluorescens ATCC 13525 and Its Biofilm: Proof of Concept on a Viscoelastic Model Food Matrix 2026. James Kamen Ngotom, Pierre Emerson Cayemitte, Ismail Fliss, Mohammed Aider. DOI 10.2139/ssrn.7156860

Maple Syrup and Bacillus velezensis based Supplement: in Vivo Study of the Impact on Growth Performance, Microbiota Composition, and Metabolic Activity in Weaned Piglets Current Microbiology, 2025. Gautier Decabooter, Luca Lo Verso, Frederic Guay, Marie Filteau, Ismail Fliss. DOI 10.1007/s00284-025-04514-5

Bioprotective Strategies to Control Listeria monocytogenes in Food Products and Processing Environments International Journal of Molecular Sciences, 2025. Omar Fliss, Ismail Fliss, Eric Biron. DOI 10.3390/ijms262110481

Exploring the genetic basis of natural resistance to microcins Microbial Genomics, 2024. Soufiane Telhig, Nguyen Phuong Pham, Laila Ben Said, Sylvie Rebuffat, Marc Ouellette, Séverine Zirah, Ismaïl Fliss. DOI 10.1099/mgen.0.001156

Synthesis and structure–activity study of the antimicrobial lipopeptide brevibacillin RSC Medicinal Chemistry, 2024. Omar Fliss, Louis-David Guay, Ismail Fliss, Éric Biron. DOI 10.1039/D4MD00612G

Targeting Enterococci with Antimicrobial Activity against Clostridium perfringens from Poultry Antibiotics, 2023. García-Vela, S., Ben Said, L., Soltani, S., Guerbaa, R., Fernández-Fernández, R., Ben Yahia, H., Ben Slama, K., Torres, C., Fliss, I.. DOI 10.3390/antibiotics12020231

Insights in the Development and Uses of Alternatives to Antibiotic Growth Promoters in Poultry and Swine Production Antibiotics, 2022. Rahman, M.R.T., Fliss, I., Biron, E.. DOI 10.3390/antibiotics11060766

Gastrointestinal Stability and Cytotoxicity of Bacteriocins From Gram-Positive and Gram-Negative Bacteria: A Comparative in vitro Study Frontiers in Microbiology, 2022. Soltani, S., Zirah, S., Rebuffat, S., Couture, F., Boutin, Y., Biron, E., Subirade, M., Fliss, I.. DOI 10.3389/fmicb.2021.780355

How Discoloration of Porcine Cruor Hydrolysate Allowed the Identification of New Antifungal Peptides Foods, 2022. Cournoyer, A., Thibodeau, J., Ben Said, L., Sanchez-Reinoso, Z., Mikhaylin, S., Fliss, I., Bazinet, L.. DOI 10.3390/foods11244035

Effects of bacterial-derived antimicrobial solutions on shelf-life, microbiota and sensory attributes of raw chicken legs under refrigerated storage condition International Journal of Food Microbiology, 2022. Zhang, L., Ben Said, L., Diarra, M.S., Fliss, I.. DOI 10.1016/j.ijfoodmicro.2022.109958

In-vitro digestion and fermentation of cranberry extracts rich in cell wall oligo/polysaccharides Journal of Functional Foods, 2022. Karboune, S., Davis, E.J., Fliss, I., Spadoni Andreani, E.. DOI 10.1016/j.jff.2022.105039

In vitro assessment of skin sensitization, irritability and toxicity of bacteriocins and reuterin for possible topical applications Scientific Reports, 2022. Soltani, S., Boutin, Y., Couture, F., Biron, E., Subirade, M., Fliss, I.. DOI 10.1038/s41598-022-08441-4

Identification of Gastrointestinal Digestion Stable Antihypertensive Fish Peptides from Atlantic Mackerel (Scomber scombrus) Journal of Medicinal Food, 2022. Hokmabadinazhad, S.A., Thibodeau, J., Fliss, I., Marette, A., Bazinet, L., Beaulieu, L.. DOI 10.1089/jmf.2021.0185

Isolation of Immunomodulatory Biopeptides from Atlantic Mackerel (Scomber scombrus) Protein Hydrolysate based on Molecular Weight, Charge, and Hydrophobicity Food and Bioprocess Technology, 2022. Abachi, S., Offret, C., Fliss, I., Marette, A., Bazinet, L., Beaulieu, L.. DOI 10.1007/s11947-022-02786-4

Comparative Study of Different Sampling Methods of Biofilm Formed on Stainless-Steel Surfaces in a CDC Biofilm Reactor Frontiers in Microbiology, 2022. Niboucha, N., Goetz, C., Sanschagrin, L., Fontenille, J., Fliss, I., Labrie, S., Jean, J.. DOI 10.3389/fmicb.2022.892181

Efficacy of bacteriocin-based formula for reducing staphylococci, streptococci, and total bacterial counts on teat skin of dairy cows Journal of Dairy Science, 2022. Bennett, S., Fliss, I., Ben Said, L., Malouin, F., Lacasse, P.. DOI 10.3168/jds.2021-21381

Evaluating the Potential and Synergetic Effects of Microcins against Multidrug-Resistant Enterobacteriaceae Microbiology Spectrum, 2022. Telhig, S., Said, L.B., Torres, C., Rebuffat, S., Zirah, S., Fliss, I.. DOI 10.1128/spectrum.02752-21

Bioactivity of mackerel peptides on obesity and insulin resistance, an in-vivo study Food Bioscience, 2022. Abachi Hokmabadinazhad, S., Songpadith, J.-P., Houde, V.P., Pilon, G., Fliss, I., Marette, A., Bazinet, L., Beaulieu, L.. DOI 10.1016/j.fbio.2022.101641

Impact of Pulsed Electric Fields and pH on Enzyme Inactivation and Bioactivities of Peptic Hydrolysates Produced from Bovine and Porcine Hemoglobin Foods, 2022. Sanchez-Reinoso, Z., Todeschini, S., Thibodeau, J., Ben Said, L., Fliss, I., Bazinet, L., Mikhaylin, S.. DOI 10.3390/foods11213313

Production of Demineralized Antibacterial, Antifungal and Antioxidant Peptides from Bovine Hemoglobin Using an Optimized Multiple-Step System: Electrodialysis with Bipolar Membrane Membranes, 2022. Abou-Diab, M., Thibodeau, J., Fliss, I., Dhulster, P., Bazinet, L., Nedjar, N.. DOI 10.3390/membranes12050512

Effects of drinking water supplementation with Lactobacillus reuteri, and a mixture of reuterin and microcin J25 on the growth performance, caecal microbiota and selected metabolites of broiler chickens Journal of Animal Science and Biotechnology, 2022. Zhang, L., Ben Said, L., Hervé, N., Zirah, S., Diarra, M.S., Fliss, I.. DOI 10.1186/s40104-022-00683-6

Determination of the Relationships between the Chemical Structure and Antimicrobial Activity of a GAPDH-Related Fish Antimicrobial Peptide and Analogs Thereof Antibiotics, 2022. Cashman-Kadri, S., Lagüe, P., Fliss, I., Beaulieu, L.. DOI 10.3390/antibiotics11030297

Impact of microcin J25 on the porcine microbiome in a continuous culture model Frontiers in Microbiology, 2022. Naimi, S., Zirah, S., Greppi, A., Lacroix, C., Rebuffat, S., Fliss, I.. DOI 10.3389/fmicb.2022.930392

Salmonella enterica subsp. enterica virulence potential can be linked to higher survival within a dynamic in vitro human gastrointestinal model Food Microbiology, 2022. Cavestri, C., Savard, P., Fliss, I., Emond-Rhéault, J.-G., Hamel, J., Kukavica-Ibrulj, I., Boyle, B., Daigle, F., Malo, D., Bekal, S., Harris, L.J., Levesque, R.C., Goodridge, L., LaPointe, G.. DOI 10.1016/j.fm.2021.103877

Bacteriocin-Based Synergetic Consortia: A Promising Strategy to Enhance Antimicrobial Activity and Broaden the Spectrum of Inhibition Microbiology Spectrum, 2022. Soltani, S., Biron, E., Said, L.B., Subirade, M., Fliss, I.. DOI 10.1128/spectrum.00406-21

Impact of conductivity on the performances of electro-acidification and enzymatic hydrolysis phases of bovine hemoglobin by electrodialysis with bipolar membranes for the production of bioactive peptides Separation and Purification Technology, 2021. Abou-Diab, M., Thibodeau, J., Fliss, I., Dhulster, P., Nedjar, N., Bazinet, L.. DOI 10.1016/j.seppur.2021.118650

Inhibitory Activity of Natural Synergetic Antimicrobial Consortia Against Salmonella enterica on Broiler Chicken Carcasses Frontiers in Microbiology, 2021. Zhang, L., Ben Said, L., Diarra, M.S., Fliss, I.. DOI 10.3389/fmicb.2021.656956

Physicochemical parameters affecting norovirus adhesion to ready-to-eat foods Applied and Environmental Microbiology, 2021. Trudel-Ferland, M., Goetz, C., Girard, M., Curt, S., Mafu, A.A., Fliss, I., Jean, J.. DOI 10.1128/AEM.01396-21

In silico analyses of the genomes of three new bacteriocin-producing bacteria isolated from animal’s faeces Archives of Microbiology, 2021. Eveno, M., Belguesmia, Y., Bazinet, L., Gancel, F., Fliss, I., Drider, D.. DOI 10.1007/s00203-020-02016-5

Murine Norovirus Interaction with Pseudomonas aeruginosa Biofilm in a Dynamic Bioreactor Food and Environmental Virology, 2021. Samandoulgou, I., Vimont, A., Fernandez, B., Fliss, I., Jean, J.. DOI 10.1007/s12560-021-09490-0

In vitro investigation of gastrointestinal stability and toxicity of 3-hyrdoxypropionaldehyde (reuterin) produced by Lactobacillus reuteri Toxicology Reports, 2021. Soltani, S., Couture, F., Boutin, Y., Ben Said, L., Cashman-Kadri, S., Subirade, M., Biron, E., Fliss, I.. DOI 10.1016/j.toxrep.2021.03.025

Adhesion of Norovirus to Surfaces: Contribution of Thermodynamic and Molecular Properties Using Virus-Like Particles Food and Environmental Virology, 2021. Samandoulgou, I., Fliss, I., Jean, J.. DOI 10.1007/s12560-021-09471-3

Bacteriocins as a new generation of antimicrobials: Toxicity aspects and regulations FEMS Microbiology Reviews, 2021. Soltani, S., Hammami, R., Cotter, P.D., Rebuffat, S., Said, L.B., Gaudreau, H., Bédard, F., Biron, E., Drider, D., Fliss, I.. DOI 10.1093/femsre/fuaa039

Biodiversity and Phylogenetic Relationships of Novel Bacteriocinogenic Strains Isolated from Animal’s Droppings at the Zoological Garden of Lille, France Probiotics and Antimicrobial Proteins, 2021. Eveno, M., Salouhi, A., Belguesmia, Y., Bazinet, L., Gancel, F., Fliss, I., Drider, D.. DOI 10.1007/s12602-020-09657-4

Stability, bioavailability and antifungal activity of reuterin during manufacturing and storage of stirred yoghurt International Dairy Journal, 2021. Pilote-Fortin, H., Ben Said, L., Cashman-Kadri, S., St-Gelais, D., Fliss, I.. DOI 10.1016/j.idairyj.2021.105141

Compatibility, Cytotoxicity, and Gastrointestinal Tenacity of Bacteriocin-Producing Bacteria Selected for a Consortium Probiotic Formulation to Be Used in Livestock Feed Probiotics and Antimicrobial Proteins, 2021. Eveno, M., Savard, P., Belguesmia, Y., Bazinet, L., Gancel, F., Drider, D., Fliss, I.. DOI 10.1007/s12602-020-09687-y

Effect of pH on the Antimicrobial Activity and Peptide Population of Pepsin Hydrolysates Derived from Bovine and Porcine Hemoglobins ACS Food Science and Technology, 2021. Sanchez-Reinoso, Z., Cournoyer, A., Thibodeau, J., Said, L.B., Fliss, I., Bazinet, L., Mikhaylin, S.. DOI 10.1021/acsfoodscitech.1c00141

Inactivation of Murine Norovirus Suspended in Organic Matter Simulating Actual Conditions of Viral Contamination Food and Environmental Virology, 2021. Jubinville, E., Girard, M., Trudel-Ferland, M., Fliss, I., Jean, J.. DOI 10.1007/s12560-021-09493-x

Activation of nrf2/ho-1 by peptide yd1 attenuates inflammatory symptoms through suppression of tlr4/myyd88/nf-κb signaling cascade International Journal of Molecular Sciences, 2021. Rahman, M.S., Alam, M.B., Kim, Y.K., Madina, M.H., Fliss, I., Lee, S.H., Yoo, J.C.. DOI 10.3390/ijms22105161

Susceptibility to Nisin, Bactofencin, Pediocin and Reuterin of Multidrug Resistant Staphylococcus aureus, Streptococcus dysgalactiae and Streptococcus uberis Causing Bovine Mastitis Antibiotics, 2021. Bennett, S., Said, L.B., Lacasse, P., Malouin, F., Fliss, I.. DOI 10.3390/antibiotics10111418

Impact of nisin and nisin‐producing lactococcus lactis ssp. Lactis on clostridium tyrobutyricum and bacterial ecosystem of cheese matrices Foods, 2021. Hassan, H., St‐gelais, D., Gomaa, A., Fliss, I.. DOI 10.3390/foods10040898

Eco-Circular Production of Demineralized Bioactive Peptides from Bovine Hemoglobin by Performing the Necessary Steps Simultaneously Using Bipolar Membrane Electrodialysis ACS Sustainable Chemistry and Engineering, 2021. Abou-Diab, M., Thibodeau, J., Fliss, I., Dhulster, P., Nedjar, N., Bazinet, L.. DOI 10.1021/acssuschemeng.1c04793