Mahmoud Rouabhia

• Centre de recherche du CHU de Québec - Université Laval
• Groupe de recherche en écologie buccale

Financements des 2 dernières années

• Fatima Zahrae Laaboudi, Doctorat en biochimie
• Manal Dahdah, Doctorat en biochimie

Encadrements des 5 dernières années

• Alexandru Paraschiv Dobriceanu, Maîtrise en sciences dentaires - endodontie - avec mémoire
• Alexis Bouffard, Maîtrise en sciences dentaires - parodontie - avec mémoire
• Atieh Sadat Abedin do, Doctorat en sciences cliniques et biomédicales
• Gilbert Thellend-Gauthier, Maîtrise en sciences dentaires - endodontie - avec mémoire
• Karolann Roussy, Maîtrise en sciences dentaires - parodontie - avec mémoire
• Maryam Bahraminia, Doctorat en microbiologie
• Maya El Choueiri, Maîtrise en sciences dentaires - avec mémoire
• Miada Abubaker Ali Osman Miada Abubaker Ali Osman, Doctorat en génie chimique
• Shujun Cui, Doctorat en sciences cliniques et biomédicales
• Shujun Cui, Stage postdoctoral en médecine dentaire

Travaux de recherche des 5 dernières années

Rare Novel Genetic Variants of the OFD1 Gene Associated With a Familial Form and a Sporadic Case of Long Bone Atypical Fractures Clinical Genetics, 2026. Marie‐Ève Boisvert, Halim Maaroufi, Rachel Laframboise, Frédéric Fournier, Suzanne N. Morin, Edith Gagnon, Claudia Gagnon, Fabrice Mac‐Way, Mahmoud Rouabhia, Louis‐Georges Ste‐Marie, Arnaud Droit, Jacques P. Brown, Laëtitia Michou. DOI 10.1111/cge.70232

The Adverse Effects of Electronic Cigarettes on Oral Health: Where Do We Stand? Dentistry Journal, 2026. Mahmoud Rouabhia. DOI 10.3390/dj14100652

Viroelixir Exhibits Cell-Line-Specific Anticancer Activity and Enhances Chemosensitivity in Oral Squamous Cell Carcinoma: Associated Changes in Apoptosis, Redox Homeostasis, and Oncogenic Signaling International Journal of Molecular Sciences, 2026. Manal Dahdah, Mahmoud Rouabhia, Hawraa Issa, Lionel Loubaki, Latifa Koussih, Mikhlid H. Almutairi, Abdelhabib Semlali. DOI 10.3390/ijms27198825

The Curcumin Analogue PAC Induces Selective Apoptosis-Related Transcriptomic Reprogramming in Oral Squamous Carcinoma Cells Life, 2026. Sara Benchekroun, Meriem Hammache, Fatiha Chandad, Mikhlid H. Almutairi, Adam Daich, Mohammed Badwelan, Mahmoud Rouabhia, Abdelhabib Semlali. DOI 10.3390/life16071041

Valorization of Goat Blood: Hydrolysate Production, Identification, Stability, and Bioavailability upon Gastrointestinal Digestion of Peptides with Dual ACE and DPP-IV Inhibitory Properties Foods, 2026. Phanthipha Laosam, Yong Yue, Pichitpon Luasiri, Saranya Suwanangul, Nattapol Pongsamai, Daranee Chokchaichamnankit, Jisnuson Svasti, Chantragan Srisomsap, Mahmoud Rouabhia, Papungkorn Sangsawad. DOI 10.3390/foods15101783

Evaluation of the Antifungal Activity of the Polyphenol Formulation Viroelixir Against Candida albicans Antibiotics, 2026. Manal Dahdah, Yasmine Ettouil, Hawraa Issa, Latifa Koussih, Mikhlid H. Almutairi, Mahmoud Rouabhia, Abdelhabib Semlali. DOI 10.3390/antibiotics15040420

Mechanistic Insights into the Anti-Virulence Effects of Viroelixir, a Phenolic Blend from Green Tea and Pomegranate, on Streptococcus mutans Antibiotics, 2026. Manal Dahdah, Vijaykumar D. Nimbarte, Mahmoud Rouabhia, Yasmine Ettouil, Hawraa Issa, Latifa Koussih, Mikhlid H. Almutairi, Abdelhabib Semlali. DOI 10.3390/antibiotics15040406

Cannabidiol (CBD) Inhibits Streptococcus oralis Growth and Biofilm Formation, While Maintaining Human Gingival Epithelial Cell Viability: An In Vitro Study International Journal of Dentistry, 2026. Celina Cruz Mainardes, Omayma Amri, Denise M. Palomari Spolidorio, Mahmoud Rouabhia. DOI 10.1155/ijod/4609857

Evaluation of the Effects of Tetrahydrocannabinol (THC) and Cannabidiol (CBD) on Gingival and Skin Keratinocyte Growth, Migration, Metabolic Activity, and Pro-Inflammatory Cytokine Secretion Biomedicines, 2025. Maryam Bahraminia, Fatima-Zahrae Laaboudi, Charlotte Romanet, Ze Zhang, Jamila Chakir, François Béland, Mahmoud Rouabhia. DOI 10.3390/biomedicines13102541

In Vitro Exposure to Vaped Tetrahydrocannabinol Increases Candida albicans (SC5314) Growth, Metabolic Activity, Biofilm Formation, and the Expression of Virulence Genes Microorganisms, 2025. Fatima-Zahrae Laaboudi, Omayma Amri, Mahmoud Rouabhia. DOI 10.3390/microorganisms13102278

New Curcumin Analogue (PAC) Inhibits Candida albicans Virulence, Restricts Its Adhesion Potential, and Relieves Oral Epithelial Cell Inflammation and Defense Mechanisms Antibiotics, 2025. Ghazoua Mezni, Hawraa Issa, Manal Dahdah, Anaïs Poulin, Adam Daïch, Abdulaziz Alamri, Mahmoud Rouabhia, Abdelhabib Semlali. DOI 10.3390/antibiotics14050495

Effect of cannabidiol (CBD), a cannabis plant derivative, against Candida albicans growth and biofilm formation Canadian Journal of Microbiology, 2025. Maryam Bahraminia, Shujun Cui, Ze Zhang, Abdelhabib Semlali, Étienne Le Roux, Kelly-Anne Giroux, Camille Lajoie, François Béland, Mahmoud Rouabhia. DOI 10.1139/cjm-2024-0034

Design of Alginate/Gelatin Hydrogels for Biomedical Applications: Fine-Tuning Osteogenesis in Dental Pulp Stem Cells While Preserving Other Cell Behaviors Biomedicines, 2024. Zied Ferjaoui, Roberto López-Muñoz, Soheil Akbari, Fatiha Chandad, Diego Mantovani, Mahmoud Rouabhia, Roberto D. Fanganiello. DOI 10.3390/biomedicines12071510

Tailoring Alginate-Gelatin Hydrogels to Precisely Modulate Osteogenesis in Dental Pulp Stem Cells While Preserving Other Cellular Behaviors 2024. Zied Ferjaoui, Roberto López-Muñoz, Soheil Akbari, Fatiha Chandad, Mantovani Diego, Mahmoud Rouabhia, Roberto Fanganiello. DOI 10.20944/preprints202403.1674.v1

Design, characterization, and release profile of a cannabidiol (CBD)-rich polyvinyl alcohol hydrogel Materials Advances, 2024. Shujun Cui, Maryam Bahraminia, Mahmoud Rouabhia, Abdelhabib Semlali, François Béland, Ze Zhang. DOI 10.1039/D4MA00398E

Synergistic Effects of New Curcumin Analog (PAC) and Cisplatin on Oral Cancer Therapy Current Issues in Molecular Biology, 2023. Abdelhabib Semlali, Sarra Beji, Ikram Ajala, Mohammed Al-Zharani, Mahmoud Rouabhia. DOI 10.3390/cimb45060319

Synergistic Effect of Anethole and Platinum Drug Cisplatin against Oral Cancer Cell Growth and Migration by Inhibiting MAPKase, Beta-Catenin, and NF-κB Pathways Pharmaceuticals, 2023. Abdelhabib Semlali, Ikram Ajala, Sarra Beji, Mohammed Mousa Al-Zharani, Mahmoud Rouabhia. DOI 10.3390/ph16050700

Development and Characterization of Functional Polylactic Acid/Chitosan Porous Scaffolds for Bone Tissue Engineering Polymers, 2022. Miada Abubaker Osman, Nick Virgilio, Mahmoud Rouabhia, Frej Mighri. DOI 10.3390/polym14235079

Oxidative Stress and Autophagy Mediate Anti-Cancer Properties of Cannabis Derivatives in Human Oral Cancer Cells Cancers, 2022. Lionel Loubaki, Mahmoud Rouabhia, Mohamed Al Zahrani, Abdullah Al Amri, Abdelhabib Semlali. DOI 10.3390/cancers14194924

Electrical stimulation promotes the wound‐healing properties of diabetic human skin fibroblasts Journal of Tissue Engineering and Regenerative Medicine, 2022. Atieh Abedin‐Do, Ze Zhang, Yvan Douville, Mireille Méthot, Julien Bernatchez, Mahmoud Rouabhia. DOI 10.1002/term.3305

Electrical Stimulation and Cellular Behaviors in Electric Field in Biomedical Research Materials, 2021. Shiyun Meng, Mahmoud Rouabhia, Ze Zhang. DOI 10.3390/ma15010165

Low-Level Laser Irradiation Promotes Proliferation and Differentiation on Apical Papilla Stem Cells Journal of Lasers in Medical Sciences, 2021. David Gutiérrez, Mahmoud Rouabhia, Javiera Ortiz, Diego Gaviria, Camilo Alfonso, Ana Muñoz, Carolina Inostroza. DOI 10.34172/jlms.2021.75

Effect of Cannabis Smoke Condensate on C. albicans Growth and Biofilm Formation Microorganisms, 2021. Neftaha Tazi, Xavier Pigeon, Jérôme Mulamba Mbuyi-Boisvert, Simon Giret, François Béland, Mahmoud Rouabhia. DOI 10.3390/microorganisms9112348

Effects of electrical stimulation on human skin keratinocyte growth and the secretion of cytokines and growth factors Biomedical Materials, 2021. Shujun Cui, Mahmoud Rouabhia, Abdelhabib Semlali, Ze Zhang. DOI 10.1088/1748-605X/ac2bba

Effects of tetrahydrocannabinols on human oral cancer cell proliferation, apoptosis, autophagy, oxidative stress, and DNA damage Archives of Oral Biology, 2021. Abdelhabib Semlali, Sarra Beji, Ikram Ajala, Mahmoud Rouabhia. DOI 10.1016/j.archoralbio.2021.105200

Expression and Polymorphism of TSLP/TSLP Receptors as Potential Diagnostic Markers of Colorectal Cancer Progression Genes, 2021. Abdelhabib Semlali, Mikhlid H. Almutairi, Abdullah Alamri, Narasimha Reddy Parine, Maha Arafah, Majid A. Almadi, Abdulrahman M. Aljebreen, Othman Alharbi, Nahla Ali Azzam, Riyadh Almutairi, Mohammad Alanazi, Mahmoud Rouabhia. DOI 10.3390/genes12091386

Effect of Electrical Stimulation on Diabetic Human Skin Fibroblast Growth and the Secretion of Cytokines and Growth Factors Involved in Wound Healing Biology, 2021. Atieh Abedin-Do, Ze Zhang, Yvan Douville, Mireille Méthot, Mahmoud Rouabhia. DOI 10.3390/biology10070641

The protective effects of the methylenetetrahydrofolate reductase rs1801131 variant among Saudi smokers Saudi Journal of Biological Sciences, 2021. Mikhlid H. Almutairi, Nouf S. Al-Numair, Narasimha Reddy Parine, Bader O. Almutairi, Abdulwahed F. Alrefaei, Mahmoud Rouabhia, Abdelhabib Semlali. DOI 10.1016/j.sjbs.2021.04.011

Electronic cigarette vapor increases Streptococcus mutans growth, adhesion, biofilm formation, and expression of the biofilm‐associated genes Oral Diseases, 2021. Mahmoud Rouabhia, Abdelhabib Semlali. DOI 10.1111/odi.13564

Effect of Dermaseptin S4 on C. albicans Growth and EAP1 and HWP1 Gene Expression Probiotics and Antimicrobial Proteins, 2021. Johan Samot, Mahmoud Rouabhia. DOI 10.1007/s12602-020-09685-0

The correlation between single nucleotide polymorphisms of the thymic stromal lymphopoietin receptor and breast cancer in a cohort of female patients in Saudi Arabia Environmental Science and Pollution Research, 2021. Semlali, A., Almutairi, M.H., Alharbi, S.N., Alamri, A.M., Alrefaei, A.F., Almutairi, B.O., Rouabhia, M.. DOI 10.1007/s11356-021-15242-1

Correlation between genetic variation in thymine DNA glycosylase and smoking behavior Gene, 2021. Almutairi, M., Rouabhia, M., Sahab Almutairi, M., Al-Zahrani, M., Al-Numair, N.S., Mohammad Alhadeq, A., Reddy Parine, N., Semlali, A.. DOI 10.1016/j.gene.2020.145092

A biocompatible polypyrrole membrane for biomedical applications RSC Advances, 2021. Cui, S., Mao, J., Rouabhia, M., Elkoun, S., Zhang, Z.. DOI 10.1039/d1ra01338f

Effect of <i>Citrus aurantium</i> L. Essential Oil on <i>Streptococcus mutans</i> Growth, Biofilm Formation and Virulent Genes Expression Antibiotics, 2021. Chahrazed Benzaid, Amine Belmadani, Lazhari Tichati, Ryad Djeribi, Mahmoud Rouabhia. DOI 10.3390/antibiotics10010054

Anethole induces anti-oral cancer activity by triggering apoptosis, autophagy and oxidative stress and by modulation of multiple signaling pathways Scientific Reports, 2021. Contant, C., Rouabhia, M., Loubaki, L., Chandad, F., Semlali, A.. DOI 10.1038/s41598-021-92456-w